Wire Guided Biopsy for Determination of Margin Status with Breast Lesions

Due to the widespread implementation of breast screening programs and improvements in diagnostic imaging, approximately 25-35% of breast cancers are non-palpable at diagnosis (Skinner et al., 2001). However, because of these breast screening programs and improvements there is an increase in the incidence of breast lesions which have to be clarified histopathologically. As well as nonpalpable breast lesions, microcalcifications that has linear configuration, asymmetric densities and structural distorsions are considered as BIRADS 4-5 lesions. Positive prediction of mammography in malign lesions (diagnosed malignancy/number of biopsy) is 30% and 90% for BIRADS 4 and BIRADS 5 lesions respectively. So, these lesions have to be clarified histopathologically. In palpable lesions fine needle or core biopsies are good standart diagnostic procedures and in nonpalpable lesions the aim is to establish histopatological diagnosis as well as complete excision of the lesion for local definitive treatment at the same time. In necessity, sentinel lymph node biopsy can be carried